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A typical intravenous dose consists of 500 mg for 2 days followed by 500 mg orally daily for an additional 5-8 days. Zithromax may interact with arsenic trioxide, cyclosporine, pimozide, tacrolimus, theophylline, warfarin, other antibiotics, antidepressants, anti- malaria medications, cholesterol -lowering medicines, ergot medicines, heart or blood pressure medications, heart rhythm medicines, HIV medicines, medicine to prevent or treat nausea and vomiting, medicines to treat psychiatric disorders. Tell your doctor all medications and supplements you use. There are no adequate studies of Zithromax in pregnant women and it is not known whether Zithromax is excreted in breast milk. Only use Zithromax in pregnant or nursing mothers when absolutely necessary. Our Zithromax Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Fungal Infections Slideshow: Fungus Among Us Take the Tummy Trouble Quiz Hepatitis C Slideshow Pictures Zithromax Consumer Information zithromax z pak Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using azithromycin and call your doctor at once if you have a serious side effect such as: diarrhea that zithromax z pak is watery or bloody; problems with zithromax headache with chest pain buy zithromax online canada and severe dizziness, fainting, fast or pounding heartbeats; nausea, upper stomach pain, itching, loss of appetite, dark. Less serious side effects may include: mild diarrhea, vomiting, constipation; stomach pain or upset; dizziness, tired feeling, mild headache; nervous feeling, sleep problems (insomnia vaginal itching or discharge; mild rash or itching; ringing in your ears, problems with hearing; or decreased sense of taste. Read the entire detailed patient monograph for Zithromax ( Azithromycin ) Learn More » Fungal Infections Slideshow: Fungus Among Us Take the Tummy Trouble Quiz Hepatitis C Slideshow Pictures Zithromax Professional Information side effects Clinical Trials Experience Because clinical trials are conducted under widely varying. In clinical trials, most of the reported adverse reactions were mild to moderate in severity and were reversible upon discontinuation of the drug. Approximately.7 of the patients from the multiple-dose clinical trials discontinued zithromax ( azithromycin ) therapy because of treatment-related adverse reactions. Serious adverse reactions included problems with zithromax angioedema and cholestatic jaundice. Most of the adverse reactions leading to discontinuation were related to the gastrointestinal tract,.g., nausea, vomiting, diarrhea, or abdominal pain. See Clinical Studies Multiple-dose Regimen Overall, the most common adverse reactions in adult patients receiving a multiple-dose regimen of zithromax were related to the gastrointestinal system with diarrhea/loose stools (5 nausea (3 and abdominal pain (3) being the most frequently reported. No other adverse reactions occurred in patients on the multiple-dose regimen of zithromax with a frequency greater than. Adverse reactions that occurred with a frequency of 1 or less included the following: Cardiovascular: Palpitations and chest pain. Gastrointestinal: Dyspepsia, flatulence, vomiting, melena, and cholestatic jaundice. Genitourinary: Monilia, vaginitis, and nephritis. Nervous System: Dizziness, headache, vertigo, and somnolence. Allergic: Rash, photosensitivity, and angioedema. Chronic therapy with 1200 mg weekly regimen The nature of adverse reactions seen with the 1200 mg weekly dosing regimen for the prevention of Mycobacterium avium infection in severely immunocompromised HIV-infected patients were similar to those seen with short-term dosing regimens. See Clinical Studies Chronic Therapy With 600 mg Daily Regimen Combined With Ethambutol The nature of adverse reactions seen with the 600 mg daily dosing regimen for the treatment of Mycobacterium avium complex infection in severely immunocompromised HIV-infected patients were similar to those seen with. Five percent of patients experienced reversible hearing impairment in the pivotal clinical trial for the treatment of disseminated MAC in patients with aids. Hearing impairment has been reported with macrolide antibiotics, especially at higher doses. Other treatment related adverse reactions occurring in 5 of subjects and seen at any time during a median.5 days of therapy include: abdominal pain (14 nausea (14 vomiting (13 diarrhea (12 flatulence (5 headache (5 and abnormal vision (5). Discontinuations from treatment due to laboratory abnormalities or adverse reactions considered related to study drug occurred in 8 of 88 (9.1) of subjects. Single 1 Gram Dose Regimen Overall, the most common adverse reactions in patients receiving a single-dose regimen of 1 gram of zithromax were related to the gastrointestinal system and were more frequently reported than in patients receiving the multiple-dose regimen. Adverse reactions that occurred in patients on the single 1 gram dosing regimen of zithromax with a frequency of 1 or greater included diarrhea/loose stools (7 nausea (5 abdominal pain (5 vomiting (2 dyspepsia (1 and vaginitis (1). Post-marketing Experience The following adverse reactions have been identified during post approval use of azithromycin. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Adverse reactions reported with azithromycin during the postmarketing period in adult and/or pediatric patients for which a causal relationship may not be established include: Allergic: Arthralgia, edema, urticaria, and angioedema. Cardiovascular: Arrhythmias, including ventricular tachycardia, and hypotension. There have been reports of QT prolongation and torsades de pointes. Gastrointestinal: Anorexia, constipation, dyspepsia, flatulence, vomiting/diarrhea pseudomembranous colitis, pancreatitis, oral candidiasis, pyloric stenosis, and tongue discoloration. General: Asthenia, paresthesia, fatigue, malaise, and anaphylaxis Genitourinary: Interstitial nephritis, acute renal failure, and vaginitis. Liver/Biliary: Abnormal liver function, hepatitis, cholestatic jaundice, hepatic necrosis, and hepatic failure. See warnings AND precautions Nervous System: Convulsions, dizziness/vertigo, headache, somnolence, hyperactivity, nervousness, agitation, and syncope.
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